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Cheap Flights from South Carolina to Ohio - Compare Flight Deals & Schedules

With plenty of flights available from South Carolina to Ohio, travelers have a wide range of choices to plan their journey more conveniently. Browse one-way fares from $48.99, round-trip fares from $128.87, and other affordable flight options that fit different budgets and preferences. Explore available schedules, compare airline services and choose the most suitable flights from South Carolina to Ohio for your travel plans.

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Cheap Flights from South Carolina to Ohio from from $48.99

Find cheap flights from South Carolina to Ohio and compare the latest fares across popular routes such as South Carolina to Ohio. Book affordable flight deals with CheapOair and save on your next trip. Call us for phone only deals at 
One Way Round Trip
MYR Myrtle Beach Thu, Sep 3
CLE Cleveland
from $49
Book Now
CHS Charleston Thu, Sep 3
CAK Akron-Canton
from $65
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CHS Charleston Sat, Aug 29
CMH Columbus
from $137
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CHS Charleston Tue, Aug 18
CVG Cincinnati
from $142
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CHS Charleston Tue, Aug 25
CLE Cleveland
from $144
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MYR Myrtle Beach Wed, Sep 9
CAK Akron-Canton
from $147
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MYR Myrtle Beach Tue, Sep 1
CMH Columbus
from $184
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MYR Myrtle Beach Fri, Aug 28
DAY Dayton
from $252
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HHH Hilton Head Fri, Nov 27
CMH Columbus
from $292
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*All fares above were last found on:
Fares are one way/round trip. Fares incl. all fuel surcharges, taxes & fees and our service fees. Displayed fares are subject to change and cannot be guaranteed at the time of booking. See all booking terms and conditions. 202607~Ref:HxyJYNIEy0CQlDTTzBNU8Q

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Better deals are one call away Call us Say and save Expires July 31, 2026. Where applicable discount applies to service fees for qualified airline tickets. Amount of service fee discount varies: maximum savings of $10 per person applied to bookings from one (1) traveler up to five (5) travelers; the maximum discount applied is $50. Promo Code and Instant Savings offers can be combined up to the amount of our service fees but cannot be used or combined with any other coupons, promotions or special offers. May be withdrawn at any time without notice. Promo code only applicable for bookings created over the phone through our call center.