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Cheap Flights from South Carolina - Explore Routes, Fares & Airline Options

With many flights from South Carolina, travelers have plenty of choices to plan their journey with greater ease and convenience. Flights operate regularly across major airlines, with a mix of nonstop and connecting options available on various routes. Browse one-way fares from $75.0, round-trip fares from $119.84, and other affordable options across a range of budgets. Review airline schedules, explore destination options and choose suitable flights from South Carolina based on your travel plans and preferences.

Trending Flight Deals from South Carolina

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One Way Round Trip
CHS Charleston Thu, Nov 26
ORL Orlando
from $75
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MYR Myrtle Beach Mon, Mar 1
HFD Hartford
from $96
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CHS Charleston Sat, Dec 12
LAS Las Vegas
from $129
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CHS Charleston Thu, Nov 19
NYC New York City
from $135
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MYR Myrtle Beach Tue, Nov 10
FLL Fort Lauderdale
from $140
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CHS Charleston Wed, Nov 11
MSY New Orleans
from $145
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CHS Charleston Wed, Nov 11
TPA Tampa
from $145
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MYR Myrtle Beach Sat, Nov 14
TPA Tampa
from $150
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CHS Charleston Thu, Nov 19
PVD Providence
from $153
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*All fares above were last found on:
Fares are one way/round trip. Fares incl. all fuel surcharges, taxes & fees and our service fees . Displayed fares are subject to change and cannot be guaranteed at the time of booking. See all booking terms and conditions . 202610~Ref:omoPreZDYUmB_wVQRzo0Rw

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Better deals are one call away Call us Say and save Expires Oct 31, 2026. Where applicable discount applies to service fees for qualified airline tickets. Amount of service fee discount varies: maximum savings of $10 per person applied to bookings from one (1) traveler up to five (5) travelers; the maximum discount applied is $50. Promo Code and Instant Savings offers can be combined up to the amount of our service fees but cannot be used or combined with any other coupons, promotions or special offers. May be withdrawn at any time without notice. Promo code only applicable for bookings created over the phone through our call center.