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Cheap Flights from Missouri to Ohio - Compare Flight Deals & Schedules

With plenty of flights available from Missouri to Ohio, travelers have a wide range of choices to plan their journey more conveniently. Browse one-way fares from $99.85, round-trip fares from $197.74, and other affordable flight options that fit different budgets and preferences. Explore available schedules, compare airline services and choose the most suitable flights from Missouri to Ohio for your travel plans.

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Cheap Flights from Missouri to Ohio from from $100

Find cheap flights from Missouri to Ohio and compare the latest fares across popular routes such as Missouri to Ohio. Book affordable flight deals with CheapOair and save on your next trip. Call us for phone only deals at 
One Way Round Trip
STL St Louis Wed, Sep 30
CLE Cleveland
from $100
Book Now
MKC Kansas City Wed, Dec 2
CMH Columbus
from $174
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MKC Kansas City Sat, Nov 21
CVG Cincinnati
from $487
Book Now
*All fares above were last found on:
Fares are one way/round trip. Fares incl. all fuel surcharges, taxes & fees and our service fees. Displayed fares are subject to change and cannot be guaranteed at the time of booking. See all booking terms and conditions. 202609~Ref:a5hty5WsEEKy9SqdqRAlHA

Good to Know Before Booking Flights from Missouri to Ohio

Plan your trip better with useful insights for flights from Missouri to Ohio, including low season, high season, and the cheapest available flight options.

Low Season

May, November, September

High Season

August, February, January

Cheapest Flight Found

$238

Book Cheap Flights from Missouri to Ohio (MO to OH)

Looking for cheap flights from Missouri to Ohio? Whether you're planning ahead or booking last minute flights from Missouri to Ohio, we help you find the best deals on airfare, hotels, and vacation packages.

Compare fares across top airlines and book flights from Missouri to Ohio with confidence — all while saving more on your travel.

Top Tips to Get Cheap Flights from Missouri to Ohio

  • Book early (30+ days): Get the best MO to OH flight deals
  • Fly midweek: Avoid weekend surcharges
  • Travel off-peak: Skip major holidays and high-demand seasons
  • Be flexible with dates: Compare fares across multiple days
  • Check alternate airports: Save more by flying from/to nearby cities
  • Use promo codes: Apply discounts at checkout
  • Book refundable fares: Travel with flexibility
  • Compare airlines: Find the lowest fare options available

Popular Destinations in Ohio

Explore top cities and attractions across Ohio. Find the best flights to Ohio and start exploring.

Best Time to Visit Ohio

Pro Tip: Book during off-season for cheaper airline tickets to Ohio.

Travel Tips for Flights from Missouri to Ohio

  • Book red eye flights from Missouri for lower fares
  • Bundle flights + hotels in Ohio to save more
  • Reserve Ohio car rentals early
  • Try book now pay later flights for flexibility

How to Get Latest Flight Deals Alerts

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Book Flights on Mobile

Book easily via mobile or app:

  • Access last minute flights to Ohio
  • Get app-only deals
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FAQs – Flights from Missouri to Ohio

Are flights from Missouri to Ohio cheaper at the airport?

No, booking online gives access to better deals and discounts.

What is the cheapest way to book flights from Missouri to Ohio?

Book early, travel midweek, and use promo codes.

Can I find last minute flights from Missouri?

Yes, deals are available depending on availability.

Are there nonstop flights available?

(Yes/No) — depending on route and availability.

Why Book With Us?
  • Best deals on cheap flights from Missouri to Ohio
  • Easy booking experience
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Book Now & Save Big!

Don’t miss out — book flights from Missouri to Ohio today and enjoy incredible savings on your travel.

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Better deals are one call away Call us Say and save Expires Sep 30, 2026. Where applicable discount applies to service fees for qualified airline tickets. Amount of service fee discount varies: maximum savings of $10 per person applied to bookings from one (1) traveler up to five (5) travelers; the maximum discount applied is $50. Promo Code and Instant Savings offers can be combined up to the amount of our service fees but cannot be used or combined with any other coupons, promotions or special offers. May be withdrawn at any time without notice. Promo code only applicable for bookings created over the phone through our call center.