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Cheap Flights from California to South Carolina - Compare Flight Deals & Schedules

With plenty of flights available from California to South Carolina, travelers have a wide range of choices to plan their journey more conveniently. Browse one-way fares from $311.42, round-trip fares from $285.99, and other affordable flight options that fit different budgets and preferences. Explore available schedules, compare airline services and choose the most suitable flights from California to South Carolina for your travel plans.

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Cheap Flights from California to South Carolina from from $311.42

Find cheap flights from California to South Carolina and compare the latest fares across popular routes such as California to South Carolina. Book affordable flight deals with CheapOair and save on your next trip. Call us for phone only deals at 
One Way Round Trip
SFO San Francisco Tue, Dec 29
GSP Greenville
from $312
Book Now
LAX Los Angeles Sat, Aug 22
MYR Myrtle Beach
from $335
Book Now
SNA Santa Ana Thu, Oct 22
CHS Charleston
from $383
Book Now
*All fares above were last found on:
Fares are one way/round trip. Fares incl. all fuel surcharges, taxes & fees and our service fees. Displayed fares are subject to change and cannot be guaranteed at the time of booking. See all booking terms and conditions. 202607~Ref:iGF3Q6SNLEC_I7MFrMdVdw

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Explore More Travel Deals from California

Explore Travel Deals to South Carolina

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Better deals are one call away Call us Say and save Expires July 31, 2026. Where applicable discount applies to service fees for qualified airline tickets. Amount of service fee discount varies: maximum savings of $10 per person applied to bookings from one (1) traveler up to five (5) travelers; the maximum discount applied is $50. Promo Code and Instant Savings offers can be combined up to the amount of our service fees but cannot be used or combined with any other coupons, promotions or special offers. May be withdrawn at any time without notice. Promo code only applicable for bookings created over the phone through our call center.