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Trending Panama Airfare Deals

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One Way Round Trip
MIA Miami
PTY Panama City
From $180.99
Jul 16, 2026
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FLL Fort Lauderdale
PTY Panama City
From $185.37
Jul 15, 2026
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DFW Dallas
PTY Panama City
From $248.41
Jul 13, 2026
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BNA Nashville
PTY Panama City
From $252.41
Aug 27, 2026
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SJU San Juan
PTY Panama City
From $253.99
Jun 30, 2026
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NYC New York City
PTY Panama City
From $378.85
Jun 10, 2026
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ORL Orlando
PTY Panama City
From $406.99
Jul 12, 2026
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LAX Los Angeles
PTY Panama City
From $436.93
Aug 31, 2026
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SFO San Francisco
PTY Panama City
From $496.93
Jun 17, 2026
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BOS Boston
PTY Panama City
From $500.99
Jun 25, 2026
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CHI Chicago
PTY Panama City
From $506.93
Jul 11, 2026
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*All fares above were last found on:
Fares are one way/round trip. Fares incl. all fuel surcharges, taxes & fees and our service fees. Displayed fares are subject to change and cannot be guaranteed at the time of booking. See all booking terms and conditions. 202605~Ref:1PIqC6yyOEu03vMAnCvgKQ

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Book Flights to Panama from USA

Reasons to Book Cheap Panama Flights
Rich in culture and beautiful in setting, Panama’s lively demeanor will inspire visitors to step out of their comfort zone with attractions like an animated festival, or an exciting boat tour.Top Things to doThe surf in Panama is plentiful with waves that will keep both intermediate and advanced riders entertained for hours.Experience an authentic Latin American carnival - a four-day long party that occurs each year before Ash Wednesday.Family Fun in PanamaTake the family on a star tour where an expert will provide extensive astronomy information.Tour the scenic Panama Canal on the Pacific Queen – Can seat 275 people with three large decks.
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