Hotels near Biosphere 2 are always on sale with CheapOair! Take a trip down to the Biosphere 2, it is the earth systems science research facility. Spread over 3.14-acre (12,700 m 2), it is owned by the University of Arizona. This structure is specifically built for to be an artificially, materially closed ecological system. Situated in Oracle, Arizona this is used by the Space Biosphere Ventures. Find great deals on cheap hotels near Biosphere 2, and count on CheapOair for all of your travel booking needs.