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Cheap Flights to Santa Cruz - Compare Airfares, Flight Times & Airlines

Travelers can choose daily flight options to Santa Cruz, with flexible choices to suit different travel needs. Browse one-way fares from $287.99, round-trip fares from $568.69, and other affordable options across a range of budgets. Flights to Santa Cruz operate regularly across major airlines, with nonstop and connecting services available throughout the week. Compare fares, review schedules, and book the right flight to Santa Cruz for your upcoming trip.

Cheap Flight Deals to Santa Cruz

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One Way Round Trip
MIA Miami Wed, Sep 9
SRZ Santa Cruz
from $287.99
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BOS Boston Mon, Sep 14
SRZ Santa Cruz
from $291.12
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CHI Chicago Thu, Aug 13
SRZ Santa Cruz
from $291.12
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FLL Fort Lauderdale Sat, Aug 8
SRZ Santa Cruz
from $292.37
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ORL Orlando Thu, Aug 20
SRZ Santa Cruz
from $300.37
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LAX Los Angeles Wed, Aug 5
SRZ Santa Cruz
from $321.37
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NYC New York City Sun, Aug 30
SRZ Santa Cruz
from $322.99
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WAS Washington DC Sun, Aug 9
SRZ Santa Cruz
from $345.99
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SFO San Francisco Tue, Nov 10
SRZ Santa Cruz
from $394.2
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*All fares above were last found on:
Fares are one way/round trip. Fares incl. all fuel surcharges, taxes & fees and our service fees. Displayed fares are subject to change and cannot be guaranteed at the time of booking. See all booking terms and conditions. 202606~Ref:FBrSWPbxJkuc1xiy33UH8Q

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Book Flights to Santa Cruz, Bolivia

Taking holidays and short city breaks is now easier than ever before with cheap flights to Santa Cruz on CheapOair.com. Well help you search, book and save on Santa Cruz flights with a huge selection of airfares across hundreds of airlines. Keep reading to learn what you can see and do after booking one of our Santa Cruz flight deals.
Santa Cruz experiences semi-tropical climate with average daytime temperatures of around 32 degree Celsius in summers and almost 21 degree Celsius in winters. The winter season in Santa Cruz is from June through August. 'Surazos' are the cooling winds which blow in the city from the Argentine pampas. These winds temper the heat. The weather in the city is majorly sunny, but there are occasional short downpours during winters.

The city of Santa Cruz is served by Viru Viru International Airport. It is an international airport handling regional, domestic, and international flights from Bolivia. Operated by Abertis, the airport offers flights to various international destinations such as Madrid, Buenos Aires, Lima, Panama City, Sucre, and more.

Places of interest in Santa Cruz
Santa Cruz de la Sierra, commonly known as Santa Cruz, is the capital city of Santa Cruz Department in eastern Bolivia. The city is perched on the bank of the Pirai River in eastern part of the country. The city is also known as a gateway to an alternative Bolivia. In terms of architectural brilliance, the tourist spots in the city are worth exploring. In addition to this, in the city, there are also several adventure options to get engaged in. It is a rapidly growing and prosperous commercial city that is just beginning to open up to tourism. The city is rapidly growing and thriving commercial city that is, at present, equally reputed in terms of tourism as well.
  • Lomas de Arena Regional Park A protected area located within the department of Santa Cruz, Lomas de Arena Regional Park covers around 14, hectares of area. Created in 199, the park encompasses tropical plains, forests, and a rich variety of fauna species as well.
  • La Plaza La Plaza is a beautiful garden located in the middle of the town. There are lots of things to do here. The area boasts several pubs and restaurants along with a cathedral as well.
  • Samaipata The village of Samaipata is located in the outskirts of the city on the foothills of the Cordillera. There are several sites boasting natural beauty located here in Samaipata. It is a wonderful place to relax and enjoy serenity.

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Cheap Flight Deals to Santa Cruz

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Round TripOne Way
CBB Cochabamba
SRZ Santa Cruz
From $171.99
Jul 23, 2026 - Jul 30, 2026
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LPB La Paz
SRZ Santa Cruz
From $219.99
Feb 24, 2027 - Mar 15, 2027
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*All fares above were last found on:
Fares are one way/round trip. Fares incl. all fuel surcharges, taxes & fees and our service fees. Displayed fares are subject to change and cannot be guaranteed at the time of booking. See all booking terms and conditions. 202606~Ref:4DDYGRi4wECuLHS_69Y_kA
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Better deals are one call away Call us Say and save Expires Jun 30, 2026. Where applicable discount applies to service fees for qualified airline tickets. Amount of service fee discount varies: maximum savings of $10 per person applied to bookings from one (1) traveler up to five (5) travelers; the maximum discount applied is $50. Promo Code and Instant Savings offers can be combined up to the amount of our service fees but cannot be used or combined with any other coupons, promotions or special offers. May be withdrawn at any time without notice. Promo code only applicable for bookings created over the phone through our call center.