server side global
  • Flights
  • Packages
  • Hotels
  • Cars
Round-trip
Coach

Refine your search by airline, by city or airport or direct flights

Bundle & Save
Book with Confidence. Trusted by 40M+ Travelers
Price Match Promise  
Found a better deal? We'll match it!
24/7 Customer Support
Speak to our travel experts anytime, anywhere.
ClubMiles Rewards
Stack points & airline miles to save.
Easy Cancellations
Convenient options online and 24/7 global concierge.

Cheap Flight Deals to Santa Cruz

Call us for phone only deals at 
Round TripOne Way
SRE Sucre
SRZ Santa Cruz
From $152.99
Jun 10, 2026 - Jun 17, 2026
Book Now
CBB Cochabamba
SRZ Santa Cruz
From $178.99
Jul 26, 2026 - Jul 27, 2026
Book Now
TJA Tarija
SRZ Santa Cruz
From $234.99
Jun 11, 2026 - Jun 14, 2026
Book Now
LPB La Paz
SRZ Santa Cruz
From $255.77
Jun 3, 2026 - Jun 8, 2026
Book Now
CIJ Cobija
SRZ Santa Cruz
From $409.75
Jun 10, 2026 - Jun 17, 2026
Book Now
*All fares above were last found on:
Fares are one way/round trip. Fares incl. all fuel surcharges, taxes & fees and our service fees. Displayed fares are subject to change and cannot be guaranteed at the time of booking. See all booking terms and conditions. 202605~Ref:VxVuC6TEn0ycJSuGGWAbJQ

What our customers say about our service?

Write a review Show more reviews
  • BrandsColin provided outstanding assistance and made the entire experience smooth and stress-free. He clearly explained everything I needed to know about the additional charges and options, ensuring there were no surprises. His professionalism, patience, and detailed guidance truly stood out. Excellent customer service from start to finish—highly appreciated!

    Read more

    Feb 16, 2026 Kilamchapbo Kilamchapbo
  • BrandsAlita is truly one of the best! Having spent years in the customer service industry myself, I recognize exceptional service when I experience it—and she absolutely delivered. She was patient, kind, respectful, knowledgeable, and impressively concise in addressing my concerns. Her professionalism and positive attitude made the entire interaction seamless and pleasant.

    Read more

    Feb 15, 2026 Pragati Shinde
  • BrandsI’m very satisfied with the experience. Eddy, the agent helping me, was courteous, knowledgeable, and a pleasure to work with. Thank you very much.

    Read more

    Dec 16, 2025 Binay Kumar Pandey

Book Flights to Santa Cruz, Bolivia

Taking holidays and short city breaks is now easier than ever before with cheap flights to Santa Cruz on CheapOair.com. Well help you search, book and save on Santa Cruz flights with a huge selection of airfares across hundreds of airlines. Keep reading to learn what you can see and do after booking one of our Santa Cruz flight deals.
Santa Cruz experiences semi-tropical climate with average daytime temperatures of around 32 degree Celsius in summers and almost 21 degree Celsius in winters. The winter season in Santa Cruz is from June through August. 'Surazos' are the cooling winds which blow in the city from the Argentine pampas. These winds temper the heat. The weather in the city is majorly sunny, but there are occasional short downpours during winters.

The city of Santa Cruz is served by Viru Viru International Airport. It is an international airport handling regional, domestic, and international flights from Bolivia. Operated by Abertis, the airport offers flights to various international destinations such as Madrid, Buenos Aires, Lima, Panama City, Sucre, and more.

Places of interest in Santa Cruz
Santa Cruz de la Sierra, commonly known as Santa Cruz, is the capital city of Santa Cruz Department in eastern Bolivia. The city is perched on the bank of the Pirai River in eastern part of the country. The city is also known as a gateway to an alternative Bolivia. In terms of architectural brilliance, the tourist spots in the city are worth exploring. In addition to this, in the city, there are also several adventure options to get engaged in. It is a rapidly growing and prosperous commercial city that is just beginning to open up to tourism. The city is rapidly growing and thriving commercial city that is, at present, equally reputed in terms of tourism as well.
  • Lomas de Arena Regional Park A protected area located within the department of Santa Cruz, Lomas de Arena Regional Park covers around 14, hectares of area. Created in 199, the park encompasses tropical plains, forests, and a rich variety of fauna species as well.
  • La Plaza La Plaza is a beautiful garden located in the middle of the town. There are lots of things to do here. The area boasts several pubs and restaurants along with a cathedral as well.
  • Samaipata The village of Samaipata is located in the outskirts of the city on the foothills of the Cordillera. There are several sites boasting natural beauty located here in Samaipata. It is a wonderful place to relax and enjoy serenity.