Get price drops, best fare alerts, deals & personalised recommendations! Explore now
  • Flights
  • Packages
  • Hotels
  • Cars
Round-trip
Coach

Refine your search by airline, by city or airport or direct flights

Here's why travelers choose CheapOair
Price Match Promise
Find great flight deals to destinations worldwide
24/7 Global Concierge
Speak to our travel experts: anytime, anywhere
ClubMiles Rewards
Earn points and air miles to maximize your rewards
Easy Cancellations
Convenient options online and 24/7 global concierge.

Cheap Flight Deals to Santa Cruz

Call us for phone only deals at 
Round TripOne Way
SRE Sucre
SRZ Santa Cruz
From $154.99
Jan 1, 2026 - Jan 8, 2026
Book Now
CBB Cochabamba
SRZ Santa Cruz
From $156.68
Jan 10, 2026 - Jan 12, 2026
Book Now
TJA Tarija
SRZ Santa Cruz
From $210.99
Feb 26, 2026 - Mar 12, 2026
Book Now
LPB La Paz
SRZ Santa Cruz
From $238.99
Dec 31, 2025 - Jan 1, 2026
Book Now
*All fares above were last found on:
Fares are one way/round trip. Fares incl. all fuel surcharges, taxes & fees and our service fees. Displayed fares are subject to change and cannot be guaranteed at the time of booking. See all booking terms and conditions. 202512~Ref:5caWo5-GoU-xupv_mXzltw

What Our Customers Say About Our Service?

Submit A Review
  • Aug 31, 2025 Ray Hobson Very reliableThis was my first time using this site and I was very please with how everything was handled. Right after I booked my flight I got a call from one of the associates letting me know i didn't pick out my seats, and choose my seat for my trip there and back from my destination. I was kept up to date in my flight information and they made sure I got my boarding pass. My trip was very stress free. I will be using them again. Thank you!

    Read More

  • Aug 28, 2025 MariaEsperanza Estilo Nicko Went Above and BeyondI had to change the return flight of two out of four passengers in our group. Because only half of the group need to travel differently, it took several calls to Iberia Airlines directly and because of the time difference, Nicko coordinated and helped me over a couple of days. Throughout the experience, he explained what he was doing and why he needs to put me on hold and why he needs to call me back the following day, He was very knowledgeable, professional and empathetic to my predicament. Nicko owned the issues and the process and was very transparent with cost and every details of the transactions. I am very grateful and because of him, I will always trust CheapOAir with my travel needs. -Maria E.E.

    Read More

  • Aug 13, 2025 Godswill Yakubu Best Travel app to check.You truly get exceptional value for a lower price, and it feels completely fair. Since I started booking with this app, I’ve come to appreciate why they stand out as the best. It’s been a wonderful experience that makes me feel understood and valued as a customer.

    Read More

Book Flights to Santa Cruz, Bolivia

Taking holidays and short city breaks is now easier than ever before with cheap flights to Santa Cruz on CheapOair.com. Well help you search, book and save on Santa Cruz flights with a huge selection of airfares across hundreds of airlines. Keep reading to learn what you can see and do after booking one of our Santa Cruz flight deals.
Santa Cruz experiences semi-tropical climate with average daytime temperatures of around 32 degree Celsius in summers and almost 21 degree Celsius in winters. The winter season in Santa Cruz is from June through August. 'Surazos' are the cooling winds which blow in the city from the Argentine pampas. These winds temper the heat. The weather in the city is majorly sunny, but there are occasional short downpours during winters.

The city of Santa Cruz is served by Viru Viru International Airport. It is an international airport handling regional, domestic, and international flights from Bolivia. Operated by Abertis, the airport offers flights to various international destinations such as Madrid, Buenos Aires, Lima, Panama City, Sucre, and more.

Places of interest in Santa Cruz
Santa Cruz de la Sierra, commonly known as Santa Cruz, is the capital city of Santa Cruz Department in eastern Bolivia. The city is perched on the bank of the Pirai River in eastern part of the country. The city is also known as a gateway to an alternative Bolivia. In terms of architectural brilliance, the tourist spots in the city are worth exploring. In addition to this, in the city, there are also several adventure options to get engaged in. It is a rapidly growing and prosperous commercial city that is just beginning to open up to tourism. The city is rapidly growing and thriving commercial city that is, at present, equally reputed in terms of tourism as well.
  • Lomas de Arena Regional Park A protected area located within the department of Santa Cruz, Lomas de Arena Regional Park covers around 14, hectares of area. Created in 199, the park encompasses tropical plains, forests, and a rich variety of fauna species as well.
  • La Plaza La Plaza is a beautiful garden located in the middle of the town. There are lots of things to do here. The area boasts several pubs and restaurants along with a cathedral as well.
  • Samaipata The village of Samaipata is located in the outskirts of the city on the foothills of the Cordillera. There are several sites boasting natural beauty located here in Samaipata. It is a wonderful place to relax and enjoy serenity.

Facts About Flying to Santa Cruz, Bolivia

Q. How many non-stop flights are available each week to Santa Cruz?

A. There are a total of 25 non-stop flights offered weekly to Santa Cruz.

Q. Which airline was the most popular choice for flights to Santa Cruz?

A. Copa Airlines, LAN Airlines was the most popular carrier for flights to Santa Cruz.

Q. During which month were the highest number of flight bookings made for travel to Santa Cruz?

A. January was the month with the highest number of flight bookings for Santa Cruz.

Q. In which month were the fewest bookings made for Santa Cruz?

A. April was the month with the least bookings for Santa Cruz.

Q. How many carriers operate flights from Santa Cruz?

A. There are currently 11 carriers operating flights departing from Santa Cruz.

Q. How many cities can I fly to non-stop from Santa Cruz?

A. You can fly non-stop to 10 cities from Santa Cruz, with varying numbers of flights available to each destination.

Q. When is the most economical month to fly to Santa Cruz?

A. January is generally considered the cheapest month to fly to Santa Cruz based on historical data.

Q. What percentage of travelers visiting Santa Cruz had children under the age of 14 accompanying them?

A. 8% of travelers traveled to Santa Cruz with kids under 14.

Q. What percentage of Santa Cruz travelers were female?

A. 50% of Santa Cruz travelers were female.

Q. What is the average length of stay for travelers in Santa Cruz?

A. On average, travelers spent approximately 14 days in Santa Cruz.

Q. How far in advance did the majority of travelers typically make their flight bookings before their travel dates?

A. Most travelers made their flight bookings approximately 5 weeks in advance of their travel dates.

Q. How many domestic and international flights depart from Santa Cruz?

A. domestic and 157 international flights depart from Santa Cruz.

Q. Which cities have non stop flights from Santa Cruz?

A. You can fly to Cochabamba, Lima, La Paz, Miami, Panama City non stop from Santa Cruz.

Q. What percentage of Santa Cruz travelers booked First or Business Class?

A. 19% of Santa Cruz travelers booked First or Business Class.

§ All of the above-mentioned facts are derived from the data of the last 3 months while the highest and lowest booking months are picked on the basis of last 12 months.